Wallingford Lab Publications

Recent Work from the Wallingford Lab:

The contribution of de novo coding mutations to meningomyelocele.
Ha et al. | Nature 2025, doi: 10.1038/s41586-025-08676-x
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The human ciliopathy protein RSG1 links the CPLANE complex to transition zone architecture.
Vazquez et al. | Nature Communications 2025, doi: 10.1038/s41467-025-61005-8

DynAPs and cytoplasmic assembly of axonemal dyneins.
Wallingford, JB et al. | Journal of Cell Science 2025, doi: 10.1242/jcs.264137

An amino acid-resolution interactome for motile cilia identifies the structure and function of ciliopathy protein complexes.
McCafferty et al. | Developmental Cell 2025, doi: 10.1016/j.devcel.2024.11.019
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Strained actin binding by the Prickle2 LIM domains and their regulation in the full-length protein.
Bejar-Padilla et al. | Molecular Biology of the Cell 2025, doi: 10.1091/mbc.E25-05-0244.

Integrative modeling reveals the molecular architecture of the intraflagellar transport A (IFT-A) complex.
McCafferty et al. |  Elife 2022, doi: 10.7554/eLife.81977.

Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contraction.
Weng, S. et al. | Cell Reports 2022 doi: 10.1016/j.celrep.2022.110666.

ARVCF catenin controls force production during vertebrate convergent extension.
​Huebner, R.J., Weng, S. et al. | Developmental Cell 2022 57, 1119-1131.

Global analysis of cell behavior and protein localization dynamics reveals region-specific functions for Shroom3 and N-cadherin during neural tube closure. 
Baldwin, A. et al. |  eLife 2022, doi: 10.7554/eLife.66704.

Mechanical heterogeneity along single cell-cell junctions is driven by lateral clustering of cadherins during vertebrate axis elongation.
Huebner, Kakkada et al. |  eLife 2021, doi: 10.7554/eLife.65390.

Hu.MAP 2.0: Integration of over 15,000 proteomic experiments builds a global compendium of human multiprotein assemblies. 
Drew, K. et al. | Molecular Systems Biology 2021, doi: 10.15252/msb.202010016.

History and Philosophy of Science:

Building Embryos.
​Wallingford, JB | Aeon 2024​

​The Anatomical Quirk That Saved Dr. No.
Wallingford, JB | Nautilus 2024​

Aristotle, Buddhist scripture, and embryology in ancient Mexico: Building inclusion by re-thinking what counts as developmental biology history.
Wallingford, JB | Development 2021, doi: 10.1242/dev.192062.
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The 200-year effort to see the embryo.
Wallingford, JB |  Science 2019 365, 758-759.

We are all developmental biologists.
Wallingford, J.B. | Developmental Cell 2019 50, 132-137.

Selected Commentaries in Developmental Biology

​Challenges and opportunities at the interface of birth defects, human genetics, and developmental biology.
​Khokha, M., Liu, K., Wallingford, J. B. Development 2020 doi: 10.1242/dev.197871.

An opportunity to address the genetic causes of birth defects.
Khokha, M.K., Mitchell, L.E., and Wallingford, J.B. Pediatric Research 2017 81, 282-285.

Developmental Biology Reviews

Cilia proteins getting to work - how do they commute from the cytoplasm to the base of cilia?
Hibbard JVK, Vázquez N, Wallingford JB | Journal of Cell Science 2022 135(17):jcs259444, doi: 10.1242/jcs.259444.

The developmental biology of kinesins.
Konjikusic, M.J., Gray, R.S., Wallingford, J.B. Developmental Biology 2020 469, 26-36.
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Planar cell polarity in development and disease.
Butler, M.T. and Wallingford, J.B. Nature Reviews, Molecular and Cell Biology 2017 18, 375-388.

Coming to consensus: A unifying model emerges for convergent extension.
Huebner, R.J. and Wallingford, J.B. Developmental Cell 2018 46, 389-396.
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"Indeed, things show up much more clearly in frogs. . ."
                                                 -Marcello Malpighi,
                                                  Letter to Giovanni Borelli, 1661